Faculty of Pharmaceutical Sciences, Teikyo University

Faculty of Pharmaceutical Sciences, Teikyo University			Publication \| Japanese
Laboratory of Drug & Gene Delivery Research

	Outline of Research		Originl homepage Laboratory of Drug and Gene Delivery Research
Drug delivery system (DDS) are being developed in order to decrease side effects and to increase therapeutic efficacy of a drug by controlling its distribution in the body. Recently, DDS is essential technology and is applied for many medicines. We have focused on the establishment of drug delivery system and strategy for cancer therapy, which are effective and less side effect. We have developed lipid-based nanoparticles of CpG oligodeoxynucleotides by changing immune-microenvironment to achieve cancer immunotherapy, and microbubble and ultrasound mediated hyperthermia for cancer therapy. In addition, we have developed microbubbles and ultrasound mediated drug and gene delivery system to the tumor tissue and brain by enhancing the blood vascular permeability. A few of our recent projects: ・Immunomodulation of nanoparticles mediated hyperthermia in cancer therapy ・Microbubbles and ultrasound mediated hyperthermia in cancer therapy ・Blood brain barrier opening using microbubbles and ultrasound for drug and gene delivery ・Anti-cancer drug delivery using microbubbles and ultrasound ・Immunomodulation by novel nanoparticelses derived from natural source

	Staff
	Professor	Ryo Suzuki, Ph.D.
	Senior Assistant Professor	Daiki Omata, Ph.D.
	Assistant professor	Risa Munakata,Ph.D.

	Fellow・Graduate Student
	Researcher	Tadamitsu Shima, Ph.D.
	Researcher	Mitsutoshi Munakata, M.D., Ph.D.
	Researcher	Toshiyuki Kudo, Ph.D.
	Researcher	Yoshiaki Yamagishi, Ph.D.
	Research Support Staff	Yuko Hino