Faculty of Pharma Sciences, Teikyo University				Publication | Japanese
Laboratory of Molecular Physiology & Pathology
	Outline of Research
The metabolic syndrome including diabetes and dyslipidemia decreases quality of life (QOL) due to the development of various symptoms in the circulatory and musculoskeletal systems. Obesity is one of the major contributing factors of metabolic syndrome, which is caused by a disorder of lifestyles and intake of unhealthy food, especially kinds of fatty acids. Therefore, preventing metabolic syndrome is a major social problem worldwide. Our goal is to make proposals on what should we eat to prevent metabolic syndrome. For this purpose, we have demonstrated the relationship between fatty acid balance and pathological states of the syndrome in adipocytes, vascular endothelial cells, and many others. We have elucidated the mechanisms of adipogenesis by using mesenchymal stem cells and preadipocytes. Moreover, we have tried to apply fragrance of food to patients, including food intake disorders. In this way, we aim to understand the pathophysiology of the metabolic syndrome and identify preventive effects of the syndrome by dietary components. To achieve our goal, we conduct our research with collaborators. Research Topics: (1) Elucidation of the relationship of fatty acids in an extracellular environment with cellular functions (2) Monitoring of internal fatty acid balance using microparticles in blood (3) Exploration of constituents derived from food that affect the size of lipid droplets (4) Improvement of QOL using fragrance of food (5) Elucidation of the role of a primary cilium in the development of obesity.
	Staff
	Professor	Gen-ichi Atsumi, Ph.D.
	Senior Assistant Professor	Masaki Saito, Ph.D.
	Assistant Professor	Kenichi Ishibashi, Ph.D.
	Fellow・Graduate Student
	Graduate Student	1 student
	Fellow	3 fellows