帝京大学薬学部 研究室ページ | English
薬化学研究室
論文リスト
1.
 Sayuri Mototani, Fumihiro Kawagoe, Kaori Yasuda, Hiroki Mano, Toshiyuki Sakaki, and Atsushi Kittaka
“The first convergent synthesis of 23,23-difluoro-25-hydroxyvitamin D3 and its 24-hydroxy derivatives: Preliminary assessment of biological activities”
Molecules 2022, 27 (16), 5352.
doi.org/10.3390/molecules27165352
2.
 Miyu Nishikawa, Naruhiro Murose, Hiroki Mano, Kaori Yasuda, Yasuhiro Isogai, Atsushi Kittaka, Masashi Takano, Shinichi Ikushiro, and Toshiyuki Sakaki
“Robust osteogenic efficacy of 2α-heteroarylalkyl vitamin D analogue AH-1 in VDR (R270L) hereditary vitamin D-dependent rickets model rats”
Sci. Rep. 2022, 12, 12517.
doi.org/10.1038/s41598-022-16819-7
3.
 Kazunari Takada, Yukino Hagiwara, Moeka Togashi, Atsushi Kittaka, Fumihiro Kawagoe, Motonari Uesugi, Shoichi Nishimoto-Kusunose, and Tatsuya Higashi
“23,25-Dihydroxyvitamin D3 is liberated as a major vitamin D3 metabolite in human urine after treatment with ?-glucuronidase: Quantitative comparison with 24,25-dihydroxyvitamin D3 by LC/MS/MS”
J. Steroid Biochem. Mol. Biol. 2022, 223, 106133.
doi.org/10.1016/j.jsbmb.2022.106133
4.
 Aileen Mendoza, Yasushi Takemoto, Kevin Tan Cruzado, Shadi Sedghi Masoud, Akiko Nagata, Ajcharapan Tantipanjaporn, Satoshi Okuda, Fumihiro Kawagoe, Ryota Sakamoto, Minami Odagi, Sayuri Mototani, Moeka Togashi, Makoto Kawatani, Harumi Aono, Hiroyuki Osada, Hayato Nakagawa, Tatsuya Higashi, Atsushi Kittaka, Kazuo Nagasawa, and Motonari Uesugi
“Controlled lipid ?-oxidation and carnitine biosynthesis by a vitamin D metabolite”
Cell Chem. Biol. 2022, 29, 1-10. doi.org/10.1016/j.chembiol.2021.08.008
5.
 Shun-suke Moriya, Yuki Yoneta, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Atsushi Kittaka, and Toru Sugiyama
“PreQ1 Facilitates DNA Strand Invasion by PNA”
Peptide Science 2021, 2022, 5, 111-112.
6.
 Yuka Mizumoto, Ryota Sakamoto, Akiko Nagata, Suzuka Sakane, Atsushi Kittaka, Minami Odagi, Masayuki Tera, and Kazuo Nagasawa
“Synthesis of C2-alkoxy-substituted 19-nor vitamin D3 derivatives: stereoselectivity and biological activity”
Biomolecules 2022, 12 (1), 69. doi.org/10.3390/biom12010069
7.
 Fumihiro Kawagoe, Sayuri Mototani, and Atsushi Kittaka
“The synthesis and biological evaluation of D-ring-modified vitamin D analogues”
Biomolecules 2021, 11 (11), 1639. doi.org/10.3390/biom11111639
8.
 Fumihiro Kawagoe, Sayuri Mototani, Kaori Yasuda, Hiroki Mano, Toshiyuki Sakaki, and Atsushi Kittaka
“Stereoselective Synthesis of 24-Fluoro-25-Hydroxyvitamin D3 Analogues and Their Stability to hCYP24A1-Dependent Catabolism”
Int. J. Mol. Sci. 2021, 22 (21), 11863. doi.org/10.3390/ijms222111863
9.
 Kaori Yasuda, Miyu Nishikawa, Hiroki Mano, Masashi Takano, Atsushi Kittaka, Shinichi Ikushiro, and Toshiyuki Sakaki
“Development of in vitro and in vivo evaluation systems for vitamin D derivatives and their application to drug discovery“
Int. J. Mol. Sci. 2021, 22 (21), 11839. doi.org/10.3390/ijms222111839
10.
 Fumihiro Kawagoe, Sayuri Mototani, and Atsushi Kittaka
“Design and synthesis of fluoro analogues of vitamin D”
Int. J. Mol. Sci. 2021, 22 (15), 8191. doi.org/10.3390/ijms22158191
11.
 Kaori Yasuda, Miyu Nishikawa, Kairi Okamoto, Kyohei Horibe, Hiroki Mano, Mana Yamaguchi, Risa Okon, Kimie Nakagawa, Naoko Tsugawa, Toshio Okano, Fumihiko Kawagoe, Atsushi Kittaka, Shinichi Ikushiro, and Toshiyuki Sakaki
“Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by Cyp24a1 and Cyp3a using Cyp24a1 knockout rats generated by CRISPR/Cas9 system”
J. Biol. Chem. 2021, 296, 100668. doi.org/10.1016/j.jbc.2021.100668
12.
 Fumihiro Kawagoe, Aileen Mendoza, Yuki Hayata, Lisa Asano, Kenjiro Kotake, Sayuri Mototani, Satoshi Kawamura, Shigeyuki Kurosaki, Yusuke Akagi, Yasushi Takemoto, Kazuo Nagasawa, Hayato Nakagawa, Motonari Uesugi, and Atsushi Kittaka
"Discovery of a Vitamin D Receptor-Silent Vitamin D Derivative That Impairs Sterol Regulatory Element-Binding Protein In Vivo"
J. Med. Chem. 2021, 64 (9), 5689-5709. doi.org/10.1021/acs.jmedchem.0c02179
13.
 Shun-suke Moriya, Hatsune Shibasaki, Misaki Kohara, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Atsushi Kittaka, and Toru Sugiyama
“Synthesis and characterization of PNA oligomers containing preQ1 as a positively charged guanine analogue”
Bioorg. Med. Chem. Lett. 2021, 39 (5), #127850.
14.
 Shunya Nakamura, Ryosuke Saito, Shohei Yamamoto, Yuta Terauchi, Atsushi Kittaka, Midori Takimoto-Kamimura, and Noriyuki Kurita
“Proposal of novel inhibitors for vitamin-D receptor: Molecular docking, molecular mechanics and ab initio molecular orbital simulations”
Biophys. Chem. 2021, 270 (3), #106540. doi.org/10.1016/j.bpc.2020.106540
15.
 Hiroshi Maruta and Atsushi Kittaka
“Chemical evolution for taming the ‘pathogenic kinase’ PAK1”
Drug Discovery Today 2020, 25 (6), 959-964. doi: org/10.1016/j.drudis.2020.03.008
16.
 Shun-suke Moriya, Yuko Sasa, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Atsushi Kittaka, and Toru Sugiyama
“An approach toward visual detection of single nucleotide polymorphism using pseudocomplementary peptide nucleic acid”
Peptide Science 2019, 2020, 56, 173-174.
17.

Akiko Nagata, Yusuke Akagi, Lisa Asano, Kenjiro Kotake, Fumihiro Kawagoe, Aileen Mendoza, Shadi Sedghi Masoud, Kosuke Usuda, Koji Yasui, Yasushi Takemoto, Atsushi Kittaka, Kazuo Nagasawa, and Motonari Uesugi
"Synthetic Chemical Probes That Dissect Vitamin D Activities"
ACS Chemical Biology 2019, 14 (12), 2851-2858.
doi: 10.1021/acschembio.9b00718
18.
 Fumihiro Kawagoe, Sayuri Mototani, Kaori Yasuda, Kazuo Nagasawa, Motonari Uesugi, Toshiyuki Sakaki, and Atsushi Kittaka
“Introduction of Fluorine Atoms to Vitamin D3 Side-chain and Synthesis of 24,24-Difluoro-25-hydroxyvitamin D3”
J. Steroid Biochem. Mol. Biol. 2019, 195 (12), #105477.
doi: 10.1016/j.jsbmb.2019.105477
19.
 Fumihiro Kawagoe, Kaori Yasuda, Sayuri Mototani, Toru Sugiyama, Motonari Uesugi, Toshiyuki Sakaki, and Atsushi Kittaka
“Synthesis and CYP24A1-Dependent Metabolism of 23-Fluorinated Vitamin D3 Analogues”
ACS Omega 2019, 4 (6), 11332-11337.
doi: 10.1021/acsomega.9b01500
20.
 Toru Sugiyama, Hatsune Shibasaki, Shun-suke Moriya, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, and Atsushi Kittaka
“PNA Oligomers Possessing PreQ1 as a Cationic Analogue of Guanine”
Peptide Science 2018, 2019, 55, 44.
21.
 Akiko Nagata, Yusuke Akagi, Shadi Sedghi Masoud, Masahiro Yamanaka, Atsushi Kittaka, Motonari Uesugi, Minami Odagi, and Kazuo Nagasawa
“Stereoselective Synthesis of Four Calcitriol Lactone Diastereomers at C23 and C25”
J. Org. Chem. 2019, 84 (12), 7630-7641.
doi: 10.1021/acs.joc.9b00403
22.
 Atsushi Kittaka
“Creation of Potent Vitamin D Receptor Agonists and Antagonists with 2α-(ω-Hydroxyalkylation) Concept to the seco-Steroid Skeleton”
CHIMIA 2018, 72 (12), 859-865. doi: 10.2533/chimia.2018.859
23.
 Atsushi Kittaka
“Novel structure development of vitamin D-derived photoreactive isomers: development of bone effect enhancement and half-life extension molecules in vivo”
Impact 2018, Vol. 2018 (10), December 2018, pp. 54-56. Publisher: Science Impact Ltd. doi: https://doi.org/10.21820/23987073.2018.10.54
24.
 Fumihiro Kawagoe, Toru Sugiyama, Kaori Yasuda, Motonari Uesugi, Toshiyuki Sakaki, and Atsushi Kittaka
“Concise Synthesis of 23-Hydroxylated Vitamin D3 Metabolites”
J. Steroid Biochem. Mol. Biol. 2019, 186 (1), 161-168. doi: 10.1016/j.jsbmb.2018. 10.010
25.
 Yuta Terauchi, Rie Suzuki, Ryosuke Takeda, Ittetsu Kobayashi, Atsushi Kittaka, Midori Takimoto-Kamimura, and Noriyuki Kurita
“Ligand Chirality Can Affect Histidine Protonation of Vitamin-D Receptor: ab initio Molecular Orbital Calculations in Water”
J. Steroid Biochem. Mol. Biol. 2019, 186 (1), 89-95. doi: 10.1016/j.jsbmb.2018.09.020
26.
 Hiroki Mano, Masashi Takano, Shinichi Ikushiro, Atsushi Kittaka, Toshiyuki Sakaki
“Novel biosensor using split-luciferase for detecting vitamin D receptor ligands based on the interaction between vitamin D receptor and coactivator”
Biochem. Biophys. Res. Commun. 2018, 505 (2), 460-465. doi:10.1016/j.bbrc.2018.09.122
27.
 Kun-Chun Chiang, Chun-Nan Yeh, Ta-Sen Yeh, Horng-Heng Juang, Li-Wei Chen, Sheng-Fong Kuo, Ming-Huang Chen, Tai C Chen, Masashi Takano, Atsushi Kittaka, Jong-Hwei S. Pang
“MART-10, a 1α,25(OH)2D3 Analog, Potently Represses Metastasis of ER+ Breast Cancer Cells with VEGF-A Overexpression”
Anticancer Res. 2018, 38 (7), 3879-3887. doi:10.21873/anticanres.12672
28.
 Daisuke Sawada, Shinji Kakuda, Akiko Takeuchi, Fumihiro Kawagoe, Midori Takimoto-Kamimura, and Atsushi Kittaka
“Effects of 2-substitution on 14-epi-19-nortachysterol-mediated biological events: Based on synthesis and X-ray co-crystallographic analysis with human vitamin D receptor”
Org. Biomol. Chem. 2018, 16 (14), 2448-2455. doi: 10.1039/C8OB00158H
29.
 Toru Sugiyama, Misaki Kohara, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, and Atsushi Kittaka
“Peptide Nucleic Acid Possessing PreQ1 as a Cationic Analogue of Guanine”
Peptide Science 2017, 2018, 54, 192-193.
30.
 Ryosuke Takeda, Rie Suzuki, Ittetsu Kobayashi, Kentaro Kawai, Atsushi Kittaka, Midori Takimoto-Kamimura, and Noriyuki Kurita
“Specific interactions between vitamin D receptor and ligand depending on its chirality: ab initio fragment molecular orbital calculations”
Chem-Bio Inform. J. 2018, 18, 32-43. doi: 10.1273/cbij.18.32
31.
 Kaori Yasuda, Eri Tohyama, Masashi Takano, Atsushi Kittaka, Miho Ohta, Shinichi Ikushiro, and Toshiyuki Sakaki
“Metabolism of 2α-[2-(tetrazol-2-yl)ethyl]-1α,25-dihydroxyvitamin D3 by CYP24A1 and biological activity of its 24R-hydroxylated metabolite”
J. Steroid Biochem. Mol. Biol. 2018, 178 (4), 333-339. doi: 10.1016/j.jsbmb.2018.02.001
32.
 Ryosuke Takeda, Ittetsu Kobayashi, Rie Suzuki, Kentaro Kawai, Atsushi Kittaka, Midori Takimoto-Kamimura, and Noriyuki Kurita
“Proposal of potent inhibitors for vitamin-D receptor based on ab initio fragment molecular orbital calculations”
Journal of Molecular Graphics and Modelling 2018, 80 (3), 320-326.
33.
 Kun-Chun Chiang, Chun-Nan Yeh, Jong-Hwei S. Pang, Jun-Te Hsu, Ta-Sen Yeh, Li-Wei Chen, Sheng-Fong Kuo, Masashi Takano, Tai C. Chen, Atsushi Kittaka, Po-Jen Hsieh, Horng-Heng Juang
“1α,25(OH)2D3 Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Metastasis After VEGF-A Stimulation”
Anticancer Res. 2017, 37 (11), 6215-6221. doi: 10.21873/anticanres.12072
34.
 Hiroki Mano, Shinichi Ikushiro, Nozomi Saito, Atsushi Kittaka, and Toshiyuki Sakaki
“Development of a Highly Sensitive in vitro System to Detect and Discriminate between Vitamin D Receptor Agonists and Antagonists Based on Split-luciferase Technique”
J. Steroid Biochem. Mol. Biol. 2018, 178 (4), 55-59. doi: 10.1016/j.jsbmb.2017.10.024
35.
 Fumihiro Kawagoe, Toru Sugiyama, Motonari Uesugi, and Atsushi Kittaka
“Recent Developments for Introducing a Hexafluoroisopropanol Unit into the Vitamin D Side Chain”
J. Steroid Biochem. Mol. Biol. 2018, 177 (3), 250-254. doi: 10.1016/j.jsbmb.2017.07.008
36.
 Toru Sugiyama, Genki Hasegawa, Chie Niikura, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, and Atsushi Kittaka
“PNA monomers fully compatible with standard Fmoc-based solid-phase synthesis of pseudocomplementary PNA”
Bioorg. Med. Chem. Lett. 2017, 27 (15), 3337-3341. doi: 10.1016/j.bmcl.2017.06.015
37.
 Toru Sugiyama, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka
“Preparation of New Fmoc 2-Thiouracil Monomer for the Synthesis of Pseudo-complementary PNA”
Peptide Science 2016, 2017, 53, 217-218.
38.
 Kun-Chun Chiang, Ta-Sen Yeh, Cheng-Cheng Huang, Yu-Chan Chang, Horng-Heng Juang, Chi-Tung Cheng, Jong-Hwei S. Pang, Jun-Te Hsu, Masashi Takano, Tai C. Chen, Atsushi Kittaka, Michael Hsiao, and Chun-Nan Yeh
“MART-10 represses cholangiocarcinoma cell growth and high vitamin D receptor expression indicates better prognosis for cholangiocarcinoma”
Sci. Rep. 2017, 7, 43773; doi: 10.1038/srep43773.
39.
 Ryosuke Takeda, Ittetsu Kobayashi, Kanako Shimamura, Hiromi Ishimura, Ryushi Kadoya, Kentaro Kawai, Atsushi Kittaka, Midori Takimoto-Kamimura and Noriyuki Kurita
“Specific interactions between vitamin-D receptor and its ligands: ab initio molecular orbital calculations in water”
J. Steroid Biochem. Mol. Biol. 2017, 171, 75-79. doi: 10.1016/j.jsbmb.2017.02.018
40.
 Masashi Takano, Kaori Yasuda, Eri Tohyama, Erika Higuchi, Toshiyuki Sakaki, and Atsushi Kittaka
“Synthesis of the CYP24A1 major metabolite of 2α-[2-(tetrazol-2-yl)ethyl]-1α,25-dihydroxyvitamin D3”
J. Steroid Biochem. Mol. Biol. 2017, 173, 75-78. doi: 10.1016/j.jsbmb. 2016.11.022.
41.
 Hiroki Mano, Miyu Nishikawa, Kaori Yasuda, Shinichi Ikushiro, Nozomi Saito, Daisuke Sawada, Shinobu Honzawa, Masashi Takano, Atsushi Kittaka, and Toshiyuki Sakaki
“Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor”
J. Steroid Biochem. Mol. Biol. 2017, 167, 61-66. doi: 10.1016/j.jsbmb.2016.09.007
42.
 Daisuke Sawada, Eiji Ochiai, Akiko Takeuchi, Shinji Kakuda, Midori Kamimura-Takimoto, Fumihiro Kawagoe, and Atsushi Kittaka
“Synthesis　of 2α- and 2β-(3-hydroxypropyl)-7,8-cis-14-epi-1α,25-dihydroxy-19-norvitamin D3 and their biological activity”
J. Steroid Biochem. Mol. Biol. 2017, 173, 79-82. doi: 10.1016/j.jsbmb.2016.09.007
43.
 Kun-Chun Chiang, Chun-Nan Yeh, Cheng-cheng Huang, Ta-Sen Yeh, Jong-Hwei S. Pang, Jun-Te Hsu, Li-Wei Chen, Sheng-Fong Kuo, Atsushi Kittaka, Tai C. Chen, and Horng-Heng Juang
“25(OH)D is effective to repress human cholangiocarcinoma cell growth through the conversion of 25(OH)D to 1α,25(OH)2D3”
Int. J. Mol. Sci. 2016, 17 (8), 1326; doi:10.3390/ijms17081326
44.
 Kun Chun Chiang, Chun-Nan Yeh, Jong-Hwei S. Pang, Jun-Te Hsu, Ta-Sen Yeh, Li-Wei Chen, Sheng-Fong Kuo, Po-Jen Hsieh, Yi-Chun Pan, Masashi Takano, Tai C. Chen, Tsui-Hsia Feng, Atsushi Kittaka, and Horng-Heng Juang
“1α,25(OH)2D3 Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Growth Through Induction of G0/G1 Cell-cycle Arrest and Apoptosis”
Anticancer Res. 2016, 36 (7), 3307-3313.
45.
 Shih-Wei Yang, Chi-Ying Tsai, Yi-Chun Pan, Chun-Nan Yeh, Jong-Hwei S. Pang, Masashi Takano, Atsushi Kittaka, Horng-Heng Juang, Tai C. Chen, and Kun-Chun Chiang
“MART-10, a newly synthesized vitamin D analog, represses metastatic potential of head and neck squamous carcinoma cells”
Drug Design, Development and Therapy, 2016, 10, 1995-2002. Doi: 10.2147/DDDT.S107256
46.
 Kun-Chun Chiang, Ta-Sen Yeh, Shin-Cheh Chen, Jong-Hwei S. Pang, Chun-Nan Yeh, Jun-Te Hsu, Li-Wei Chen, Sheng-Fong Kuo, Masashi Takano, Atsushi Kittaka, Tai C. Chen, Chi-Chin Sun, and Horng-Heng Juang
“The vitamin D analog, MART-10, attenuates triple negative breast cancer cells metastatic potential”
Int. J. Mol. Sci., 2016, 17 (4), 606-619. Doi: 10.3390/ijms17040606
47.
 Yotaro Matsumoto, Akihiro Ito, Motonari Uesugi, and Atsushi Kittaka
“Efficient N-Acyldopamine Synthesis”
Chem. Pharm. Bull. 2016, 64 (7), 935-940. doi.org/10.1248/cpb.c16-00162
48.
 Toru Sugiyama, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka
“Peptide Nucleic Acid with a Lysine side chain at the β-Position: Synthesis and Application for DNA Cleavage”
Chem. Pharm. Bull. 2016, 64 (7), 817-823. doi.org/10.1248/cpb.c16-00191
49.
 Daisuke Sawada, Shinji Kakuda, Midori Kamimura-Takimoto, Akiko Takeuchi, Yotaro Matsumoto, and Atsushi Kittaka
“Revisiting the 7,8-cis-vitamin D3 derivatives: synthesis, evaluating the biological activity, and study of the binding configuration”
Tetrahedron 2016, 72 (22), 2838-2848. doi:10.1016/j.tet.2016.03.081
50.
 Kun Chun Chiang, Chi-Chin Sun, Ming-Huang Chen, Chi-Ying Huang, Jun-Te Hsu, Ta-Sen Yeh, Li-Wei Chen, Sheng-Fong Kuo, Horng-Heng Juang, Masashi Takano, Atsushi Kittaka, Tai C. Chen, Chun Nan Yeh, Jong-Hwei S. Pang
“MART-10, the new brand of 1?,25(OH)2D3 analog, is a potent anti-angiogenic agent in vivo and in vitro”
J. Steroid Biochem. Mol. Biol. 2016, 155 (Part A), 26-34. doi: 10.1016/j.jsbmb.2015.09.022
51.
 Masashi Takano, Kaori Yasuda, Erika Higuchi, Eri Tohyama, Akiko Takeuchi, Toshiyuki Sakaki, and Atsushi Kittaka
“Synthesis, metabolism, and biological activity of 2-[3-(tetrazolyl)propyl]-1?,25-dihydroxy-19-norvitamin D3”
J. Steroid Biochem. Mol. Biol. 2016(Oct. 31), 164(1), 40-44. doi: 10.1016/j.jsbmb.2015.07.016
52.
 Toru Sugiyama, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka
“Synthesis of PNA Oligomers Containing Modified Deazaguanines for the Development of Functional PNA”
Peptide Science 2015, 2016, 52, 307-308.
53.
 Takashi Misawa, Momoko Yorioka, Yosuke Demizu, Tomomi Noguchi-Yachide, Nobumichi Ohoka, Megumi Kurashima-Kinoshita, Hitomi Motoyoshi, Hisao Nojiri, Atsushi Kittaka, Makoto Makishima, Mikihiko Naito, Masaaki Kurihara
“Effects of alkyl side chains and terminal hydrophilicity on vitamin D receptor (VDR) agonistic activity based on the diphenylpentane skeleton”
Bioorg. Med. Chem. Lett. 2015, 25 (22), 5362-5366. doi: 10.1016/j.bmcl.2015.09.030
54.
 Hiroki Mano, Miyu Nishikawa, Kaori Yasuda, Shinichi Ikushiro, Nozomi Saito, Masashi Takano, Atsushi Kittaka, and Toshiyuki Sakaki
“Development of novel bioluminescent sensor to detect and discriminate between vitamin D receptor agonists and antagonists in living cells”
Bioconjugate Chemistry 2015, 26 (10), 2038-2045. doi: 10.1021/acs.bioconjchem.5b00433
55.
 Tai C. Chen, Toshiyuki Sakaki, and Atsushi Kittaka
“Vitamin D & Analogues in Cancer Prevention & Therapy Research”
Adjacent Government, 2015, Issue 7 August, 66-67.
56.
 Kun-Chun Chiang, Sheng-Fong Kuo, Chih-Hung Chen, Sohching Ng, Shu-Fu Lin, Chun-Nan Yeh, Li-Wei Chen, Masashi Takano, Tai C. Chen, Horng-Heng Juang, Atsushi Kittaka, Jen-Der Lin, Jong-Hwei S. Pang
“MART-10, the Vitamin D analog, is a potent drug to inhibit anaplastic thyroid cancer cell metastatic potential”
Cancer Letters 2015, 369 (1), 76-85. doi: 10.1016/j.canlet.2015.07.024
57.
 Kun-Chun Chiang, Cho-Li Yen, Chun-Nan Yeh, Jun-Te Hsu, Li-Wei Chen, Sheng-Fong Kuo, Shang-Yu Wang, Chi-Chin Sun, Atsushi Kittaka, Tai C. Chen, Ta-Sen Yeh, Shu-Yuan Hsu, Horng-Heng Juang
“Hepatocellular carcinoma cells express 25(OH)D-1?-hydroxylase and are able to convert 25(OH)D to 1?,25(OH)2D, leading to the 25(OH)D-induced growth inhibition”
J. Steroid Biochem. Mol. Biol. 2015, 154, 47-52. doi: 10.1016/j.jsbmb.2015.06.008
58.
 Yotaro Matsumoto, Atsushi Kittaka, and Tai C. Chen
“19-Norvitamin D Analogs for Breast Cancer Therapy”
Can. J. Physiol. Pharmacol. 2015, 93 (5), 333-348. doi: 10.1139/cjpp-2014-0452
59.
 Toru Sugiyama, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka
“Modified Deazaguanines for the Synthesis of PNA”
Peptide Science 2014, 2015, 51, 87-88.
60.
 Masashi Takano, Daisuke Sawada, Kaori Yasuda, Miyu Nishikawa, Akiko Takeuchi, Ken-ichiro Takagi, Kyohei Horie, G. Satyanarayana Reddy, Tai C. Chen, Toshiyuki Sakaki, and Atsushi Kittaka; Synthesis and metabolic studies of 1alpha,2alpha,25-, 1alpha,4alpha,25- and 1alpha,4beta,25-trihydroxyvitamin D3. J. Steroid Biochem. Mol. Biol. 2015, 148, 34-37. doi: 10.1016/j.jsbmb.2014.09.021
61.
 Yasutada Imamura, Suzuka Tsuboi, Toru Sugiyama, Atsushi Kittaka, and Yonchol Shin; A Peptide Nucleic Acid to Reduce Type I Collagen Production by Fibroblast Cells. Open Journal of Medicinal Chemistry 2015, 5(1), 1-8. doi: org/10.4236/ojmc.2015.51001
62.
 Masashi Takano, Erika Higuchi, Kazunari Higashi, Keisuke Hirano, Akiko Takeuchi, Daisuke Sawada, and Atsushi Kittaka; Synthesis and Preliminary Biological Evaluation of 2-[3-(Tetrazolyl)propyl]-1alpha,25-dihydroxy-19-norvitamin D3. Heterocycles 2015, 90(2), 1274-1287. doi: 10.3987/COM-14-S(K)108
63.
 Tai C. Chen, Atsushi Kittaka, and Gunnar Norstedt; Vitamin D against Cancer. International Innovation 2014, 157, 18-19.
64.
 Kun-Chun Chiang, Chun-Nan Yeh, Jun-Te Hsu, Yi-Yin Jan, Li-Wei Chen, Sheng-Fong Kuo, Masashi Takano, Atsushi Kittaka, Tai-C Chen, Wen-Tsung Chen, Jong-Hwei S.Pang, Ta-Sen Yeh, and Horng-Heng Juang; The Vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial-mesenchymal transition in pancreatic cancer cells. Cancer Letters 2014, 354(2), 235-244. doi: 10.1016/j.canlet.2014.08.019
65.
 Daisuke Sawada and Atsushi Kittaka; Synthesis and properties of 14-epi-1alpha,25-dihydroxy-19-nortachysterol and its 2-substituted derivatives. Current Topics in Medicinal Chemistry 2014, 14(21), 2454-2459. DOI:10.2174/1568026615666141208103741
66.
 Kun-Chun Chiang, Chun-Nan Yeh, Kun-Ju Lin, Li-Jen Su, Tzu-Chen Yen, Jong-Hwei S. Pang, Atsushi Kittaka, Chi-Chin Sun, Miin-Fu Chen, Yi-Yin Jan, Horng-Heng Juang, Ta-Sen Yeh, and Tai C. Chen; Chemopreventive and Chemotherapeutic Effect of Dietary Supplementation of Vitamin D on Cholangiocarcinoma in a Chemical-Induced Animal Model. Oncotarget 2014, 5 (11), 3849-3861.
67.
 Toru Sugiyama, Keiko Kuwata, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka; Sequence-Specific Cleavage of DNA by beta-Peptide Nucleic Acid Bearing a Pendant Metal Complex. Peptide Science 2013, 2014, 50, 369-370.
68.
 Masashi Takano, Saori Ohya, Kaori Yasuda, Miyu Nishikawa, Akiko Takeuchi, Daisuke Sawada, Toshiyuki Sakaki, and Atsushi Kittaka; Synthesis and Biological Activity of 1alpha,2alpha,25-Trihydroxyvitamin D3: Active Metabolite of 2alpha-(3-Hydroxypropoxy)-1alpha,25-dihydroxyvitamin D3 by Human CYP3A4; Chem. Pharm. Bull. 2014, 62(2), 182-184.
69.
 Kun-Chun Chiang, Shin-Cheh Chen, Chun-Nan Yeh, Jong-Hwei S. Pang, Shih-Che Shen, Jun-Te Hsu, Yu-Yin Liu, Li-Wei Chen, Sheng-Fong Kuo, Masashi Takano, Atsushi Kittaka, Chi-Chin Sun, Horng-Heng Juang, and Tai C. Chen; MART-10, a Less Calcemic Vitamin D Analog, Is More Potent Than 1alpha,25-Dihydroxyvitamin D3 in Inhibiting the Metastatic Potential of MCF-7 Breast Cancer Cells in Vitro; J. Steroid Biochem. Mol. Biol. 2014, 139(1), 54-60.
70.
 Miki Matsuo, Asami Hasegawa, Masashi Takano, Hiroshi Saito, Shinji Kakuda, Kenichiro Takagi, Eiji Ochiai, Kyohei Horie, Midori Takimoto-Kamimura, Kazuya Takenouchi, Daisuke Sawada, and Atsushi Kittaka; Design and synthesis of 2alpha-(tetrazolylethyl)-1alpha,25-dihydroxyvitamin D3 as a high affinity ligand for vitamin D receptor. J. Steroid Biochem. Mol. Biol. 2014, 144, 201-203. doi: 10.1016/j.jsbmb.2013.09.001
71.
 Toshiyuki Sakaki, Kaori Yasuda, Atsushi Kittaka, Keiko Yamamoto, and Tai C. Chen; CYP24A1 as a Potential Target for Cancer Therapy; Anti-Cancer Agents Med. Chem. 2014, 14(1), 97-108.
72.
 Kunchun Chiang, Chun-Nan Yeh, Jun-Te Hsu, Li-Wei Chen, Sheng-Fong Kuo, Chi-Chin Sun, Cheng-Cheng Huang, Jong-Hwei S. Pang, John N. Flanagan, Masashi Takano, Atsushi Kittaka, Horng-Heng Juang, Shih-Wei Yang and Tai C. Chen; MART-10, a Novel Vitamin D Analog, Inhibits Head and Neck Squamous Carcinoma Cells Growth through Cell Cycle Arrest at G0/G1 with Upregulation of p21 and p27 and Downregulation of Telomerase; J. Steroid Biochem. Mol. Biol. 2013, 138(11), 427-434.
73.
 Miki Matsuo, Asami Hasegawa, Masashi Takano, Hiroshi Saito, Shinji Kakuda, Takayuki Chida, Ken-ichiro Takagi, Eiji Ochiai, Kyohei Horie, Yoshifumi Harada, Midori Takimoto-Kamimura, Kazuya Takenouchi, Daisuke Sawada, and Atsushi Kittaka; Synthesis of 2alpha-Heteroarylalkyl Active Vitamin D3 with Therapeutic Effect on Enhancing Bone Mineral Density in vivo; ACS Med. Chem. Lett. 2013, 4(7), 671-674.
74.
 Toru Sugiyama, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka; Synthesis of beta-Chiral Peptide Nucleic Acids Bearing Lysine Side Chains; Peptide Science 2012, 2013, 49, 385-386.
75.
 Kun-Chun Chiang, Chun-Nan Yeh, Jun-Te Hsu, Ta-sen Yeh, Yi-yan Jan, Chun-Te Wu, Huang-Yang Chen, Shyh-Chuan Jwo, Masashi Takano, Atsushi Kittaka, Horng-Heng Juang and Tai C. Chen; Evaluation of the Potential Therapeutic Role of a New Generation of Vitamin D Analog, MART-10, in Human Pancreatic Cancer Cells in Vitro and in Vivo; Cell Cycle 2013, 12(8), 1316-1325.
76.
 Daisuke Sawada, Yuya Tsukuda, Hiroshi Saito, Kenichiro Takagi, Shinji Kakuda, Midori Takimoto-Kamimura, Eiji Ochiai, Kazuya Takenouchi, and Atsushi Kittaka; Synthesis of 14-epi-2alpha-hydroxypropoxy-1alpha,25-dihydroxy-19-nortachysterol and its hVDR binding; J. Steroid Biochem. Mol. Biol. 2013, 136, 27-29.
77.
 Hiroshi Saito, Kenichiro Takagi, Kyohei Horie, Shinji Kakuda, Midori Takimoto-Kamimura, Eiji Ochiai, Takayuki Chida, Yoshifumi Harada, Kazuya Takenouchi, and Atsushi Kittaka; Synthesis of Novel C-2 Substituted Vitamin D Derivatives Having Ringed Side Chains and Their Biological Evaluation on Bone; J. Steroid Biochem. Mol. Biol. 2013, 136, 3-8.
78.
 Toru Sugiyama and Atsushi Kittaka; Chiral Peptide Nucleic Acids with a Substituent in the N-(2-Aminoethy)glycine Backbone; Molecules 2013, 18(1), 287-310.
79.
 Kun-Chun Chiang, Chun-Nan Yeh, Shin-Cheh Chen, Shih-Che Shen, Jun-Te Hsu, Ta-sen Yeh, Jong-Hwei S. Pang, Li-Jen Su, Masashi Takano, Atsushi Kittaka, Horng-Heng Juang, and Tai C. Chen; MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1alpha,25-Dihydroxyvitamin D3 in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells; Evidence-Based Complementary and Alternative Medicine 2012, Vol. 2012, Article ID 310872, 10 pages. doi: 10.1155/2012/310872.
80.
 Human Cytochrome P450-dependent differential metabolism among three 2alpha-substituted-1alpha,25-dihydroxyvitamin D3 analogs; Yasuda, K., Ikushiro, S., Kamakura, M., Takano, M., Saito, N., Kittaka, A., Chen, T.C., Ohta, M. and Sakaki, T.; J. Steroid Biochem. Mol. Biol., 133(1), 84-92 (2013).
81.
 Potent 19-norvitamin D analogs are potential candidates for prostate and liver cancer therapy; Kittaka, A., Yoshida, A., Chiang, K.-C., Takano, M., Sawada, D., Sakaki, T. and Chen, T.C.; Future Med. Chem. 4(16), (2012) 2049-2065.
82.
 Synthesis and biological activities of 1alpha,4alpha,25- and 1beta,4beta,25-trihydroxyvitamin D3 and their metabolism by human CYP24A1 and UDP-glucuronosyltransferase; Sawada, D., Tsukuda, Y., Yasuda, K., Sakaki, T., Saito, H., Takagi, K., Takenouchi, K., Chen, T.C., Reddy, G.S. and Kittaka, A.; Chem. Pharm. Bull. 60(10),1343-1346 (2012).
83.
 Toru Sugiyama, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka “Synthesis of beta-Chiral Peptide Nucleic Acids and Their DNA Binding Properties” Peptide Science 2011, 2012, 48, 353-354.
84.
 Daisuke Sawada, Tomoyuki Katayama, Yuya Tsukuda, Nozomi Saito, Hiroshi Saito, Shinji Kakuda, Midori Takimoto-Kamimura, Kazuya Takenouchi, and Atsushi Kittaka “The Difference between 14-Epi-previtamin D3 and 14-Epi-19-norprevitamin D3: Their Synthesis and Binding Affinity for Human VDR” Anticancer Res. 2012, 32(1), 319-326.
85.
 Go Kumagai, Masashi Takano, Kanako Shindo, Daisuke Sawada, Nozomi Saito, Hiroshi Saito, Sshinji Kakuda, Ken-ichiro Takagi, Midori Takimoto-Kamimura, Kazuya Takenouchi, Tai C. Chen and Atsushi Kittaka “C15-Functionalized 16-Ene-1alpha,25-dihydroxyvitamin D3 is a New Vitamin D Analog with Unique Biological Properties” Anticancer Res. 2012, 32(1), 311-318.
86.
 Toru Sugiyama, Yasutada Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano and Atsushi Kittaka “beta-PNA: Peptide Nucleic Acid (PNA) with a Chiral Center at the beta-Position of the PNA Backbone” Bioorg. Med. Chem. Lett. 2011, 21(24), 7317-7320.
87.
 Tai C. Chen, Toshiyuki Sakaki, Keiko Yamamoto, and Atsushi Kittaka “The Roles of Cytochrome P-450 Enzymes in Prostate Cancer Development and Treatment” Anticancer Res. 2012, 32(1), 291-298.
88.
 Kun-Chun Chiang, Chun-Nan Yeh, Huang-Yang Chen, Jim-ming Lee, Horng-Heng Juang, Miin-Fu Chen, Masashi Takano, Atsushi Kittaka, and Tai C. Chen “19-Nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 (MART-10) is a Potent Cell Growth Regulator with Enhanced Chemotherapeutic Potency in Liver Cancer Cells” Steroids 2011, 76(13), 1513-1519.
89.
 Diego Iglesias-Gato, Shasha Zheng, John N. Flanagan, Lan Jiang, Atsushi Kittaka, Toshiyuki Sakaki, Keiko Yamamoto, Toshimasa Itoh, Nathan K. LeBrasseur, Gunnar Norstedt, Tai C. Chen “Substitution at Carbon 2 of 19-Nor-1alpha,25-dihydroxyvitamin D3 with 3-Hydroxypropyl Group Generates an Analog with Enhanced Chemotherapeutic Potency in PC-3 Prostate Cancer Cells” J. Steroid Biochem. Mol. Biol. 2011, 127(3-5), 269-275.
90.
 Eiji Munetsuna, Sachie Nakabayashi, Rie Kawanami, Kaori Yasuda, Miho Ohta, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki “Mechanism of the Anti-proliferative Action of 25-Hydroxy-19-nor-vitamin D3 in Human Prostate Cells” J. Mol. Endocrinol. 2011, 47(2), 209-218.
91.
 Tai C. Chen and Atsushi Kittaka “Novel Vitamin D Analogs for Prostate Cancer Therapy” International Scholarly Research Network (ISRN) Urology 2011, Vol. 2011, Article ID 301490, 9 pages, doi:10.5402/2011/301490.
92.
 Yasuda, K., Hayashi, K., Ikushiro, S., Kamakura, M., Munetsuna, E., Sugimoto, H., Shiro, Y., Kittaka, A., Ohta, M., and Sakaki, T; Production of an Active Form of Vitamin D3 by a Recombinant Actinomycete Expressing Genetically Engineered CYP105A1. Vitamins (Japanese) 2011, 85(3), 109-114.
93.
 Toru Sugiyama, Yasutaka Imamura, Yosuke Demizu, Masaaki Kurihara, Masashi Takano, and Atsushi Kittaka “Synthesis of 4-Substituted Chiral PNA Monomers” Peptide Science 2010, 2011, 47, 284.
94.
 Kanako Shindo, Go Kumagai, Masashi Takano, Daisuke Sawada, Nozomi Saito, Hiroshi Saito, Shinji Kakuda, Ken-ichiro Takagi, Eiji Ochiai, Kyohei Horie, Midori Takimoto-Kamimura, Seiichi Ishizuka, Kazuya Takenouchi, and Atsushi Kittaka “New C15-Substituted Active Vitamin D3” Org. Lett. 2011, 13(11), 2852-2855.
95.
 Daisuke Sawada, Yuya Tsukuda, Hiroshi Saito, Shinji Kakuda, Midori Takimoto-Kamimura, Eiji Ochiai, Kazuya Takenouchi, and Atsushi Kittaka “Development of 14-epi-19-Nortachysterol and Its Unprecedented Binding Configuration for the Human Vitamin D Receptor” J. Am. Chem. Soc. 2011, 133(18), 7215-7221.
96.
 Hiroshi Saitoh, Takayuki Chida, Kenichiro Takagi, Kyohei Horie, Yoshiyuki Sawai, Yuko Nakamura, Yoshifumi Harada, Kazuya Takenouchi, and Atsushi Kittaka “Synthesis of C-2 Substituted Vitamin D Derivatives Having Ringed Side Chains and Biological Evaluation, Especially Biological Effect on Bone by Modification at C-2 Position” Org. Biomol. Chem. 2011, 9(10), 3954-3964.
97.
 Yosuke Demizu, Aki Nakatsu, Yukiko Sato, Shinobu Honzawa, Atsushi Yamashita, Takayuki Sugiura, Atsushi Kittaka, Shigeaki Kato, Haruhiro Okuda and Masaaki Kurihara “Facile Synthesis of Stereoisomers of the Non-Secosteroidal Ligand LG190178 and their Evaluation Using the Mutant Vitamin D Receptor” Lett. Org. Chem. 2011, 8(1), 43-47.
98.
 Keiko Hayashi, Kaori Yasuda, Hiroshi Sugimoto, Shinichi Ikushiro, Masaki Kamakura, Atsushi Kittaka, Ronald L. Horst, Tai C. Chen, Miho Ohta, Yoshitsugu Shiro, and Toshiyuki Sakaki
“Three-step Hydroxylation of Vitamin D3 by a Genetically Engineered CYP105A1” FEBS J. 2010, 277(19), 3999-4009.
99.
 Atsushi Kittaka, Hideki Hara, Kaori Yasuda, Masashi Takano, Midori A. Arai, Daisuke Sawada, Hiroshi Saito, Kazuya Takenouchi, Tai C. Chen, and Toshiyuki Sakaki “Studies on the Synthesis and Metabolism of 14-epi-2alpha-(3-Hydroxypropyl)-19-norvitamin D3 and Its 2beta-Isomer” Heterocycles 2010, 82(1), 649-661.
100.
 Daisuke Sawada, Tomoyuki Katayama, Yuya Tsukuda, Nozomi Saito, Hiroshi Saito, Ken-ichiro Takagi, Eiji Ochiai, Seiichi Ishizuka, Kazuya Takenouchi, and Atsushi Kittaka “Synthesis of 2alpha- and 2beta-Substituted-14-epi-previtamin D3 and Their Genomic Activity” Tetrahedron 2010, 66(29), 5407-5423.
101.
 Toru Sugiyama, Keiko Ninomiya, Yasutada Imamura, Masaaki Kurihara, Masashi Takano and Atsushi Kittaka “Sequence-Specific Cleavage of DNA by Peptide Nucleic Acids Conjugated with Metal Complexes” Peptide Science 2009, 2010, 425-426.
102.
 Daisuke Sawada, Yuya Tsukuda, Hiroshi Saito, Ken-ichiro Takagi, Eiji Ochiai, Seiichi Ishizuka, Kazuya Takenouchi, and Atsushi Kittaka “Synthesis of 2beta-Substituted-14-epi-previtamin D3 and Testing of Its Genomic Activity” J. Steroid Biochem. Mol. Biol. 2010, 121(1-2), 20-24.
103.
 Daisuke Sawada, Yuya Tsukuda, Hiroshi Saito, Ken-ichiro Takagi, Kyouhei Horie, Eiji Ochiai, Kazuya Takenouchi, and Atsushi Kittaka “Synthesis and Biological Evaluation of 4-Substituted Vitamin D and 14-Epi-Previtamin D Analogs” Chem. Pharm. Bull. 2009, 57(12), 1431-1433.
104.
 Daisuke Sawada, Tomoyuki Katayama, Yuya Tsukuda, Nozomi Saito, Masashi Takano, Hiroshi Saito, Ken-ichiro Takagi, Eiji Ochiai, Seiichi Ishizuka, Kazuya Takenouchi, and Atsushi Kittaka “Synthesis of 2alpha-Substituted-14-epi-previtamin D3 and Its Genomic Activity” Bioorg. Med. Chem. Lett. 2009, 19(18), 5397-5400.
105.
 Shinobu Honzawa, Naoyuki Takahashi, Atsushi Yamashita, Takayuki Sugiura, Masaaki Kurihara, Midori A. Arai, Shigeaki Kato, and Atsushi Kittaka “Synthesis of a 1alpha-C-Methyl Analogue of 25-Hydroxyvitamin D3: Interaction with a Mutant Vitamin D Receptor Arg274Leu” Tetrahedron 2009, 65(34), 7135-7145.
106.
 Nozomi Saito, Yoshitomo Suhara, Daisuke Abe, Tatsuya Kusudo, Miho Ohta, Kaori Yasuda, Toshiyuki Sakaki, Shinobu Honzawa, Toshie Fujishima, and Atsushi Kittaka “Synthesis of 2alpha-Propoxy-1alpha,25-dihydroxyvitamin D3 and Comparison of Its Metabolism by Human CYP24A1 and Rat CYP24A1” Bioorg. Med. Chem. 2009, 17(13), 4296-4301.
107.
 Toru Sugiyama, Yasutada Imamura, Masaaki Kurihara and Atsushi Kittaka “Cooperative Strand Invasion of Peptide Nucleic Acid” Peptide Science 2008, 2009, 481-489.
108.
 Kittaka, A., Saito, N., Takenouchi, K., and Ishizuka, S; Structure-Activity Relationship Study on TEI-9647 and TEI-9648: Aiming at the Strongest VDR Antagonist with Modification of the 2alpha and 24 Positions.Vitamins (Japanese） 2009, 83(10), 569-579.
109.
 John N. Flanagan, Shasha Zheng, Kun-Chun Chiang, Atsushi Kittaka, Toshiyuki Sakaki, Sachie Nakabayashi, Remco A. Spanjaard, Kelly S. Persons, Jeffrey S. Mathieu, Michael F. Holick, and Tai C. Chen “Evaluation of 19-Nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 As a Therapeutic Agent for Androgen-dependent Prostate Cancer” Anticancer Res. 2009, 29(9), 3547-3553.
110.
 Atsushi Kittaka, Hideki Hara, Masashi Takano, Daisuke Sawada, Midori A. Arai, Kenichiro Takagi, Takayuki Chida, Yoshifumi Harada, Hiroshi Saito, Kazuya Takenouchi, Seiichi Ishizuka, Keiko Hayashi, Shinichi Ikushiro, Toshiyuki Sakaki, Takayuki Sugiura, and Tai C. Chen “Synthesis and Biological Activities of 14-epi-MART-10 and 14-epi-MART-11: Implications for Cancer and Osteoporosis Treatment” Anticancer Res. 2009, 29(9), 3563-3569.
111.
 「Seco-ステロイド骨格の構造展開と核内受容体を介する生物活性」
橘高敦史
薬学雑誌 128 (9) 1235-1250 (2008).
112.
 "The 2α-(3-hydroxypropyl) group as an active motif in vitamin D3 analogues as agonists of the mutant vitamin D receptor (Arg274Leu)"
Honzawa, S., Yamamoto, Y., Yamashita, A., Sugiura, T., Kurihara, M., Arai, M.A., Kato, S., Kittaka, A.
Bioorg. Med. Chem. 16 (6) 3002-3024 (2008).
113.
 "(2S,2'R)-Analogue of LG190178 Is a Major Active Isomer"
Hakamata, W., Sato, Y., Okuda, H., Honzawa, S., Saito, N., Kishimoto, S., Yamashita, A., Sugiura, T., Kittaka, A., Kurihara, M.
Bioorg. Med. Chem. Lett. 18 (1) 120-123 (2008).
114.
 Recognition of Longer Duplex DNA by Cooperative Strand Invasion;
Sugiyama, T., Imamura, Y., Kurihara, M., Kittaka, A.
Nucleic Acids Symp. Ser. (No. 51) 269-270 (2007).
115.
 「ビタミンD3-26,23-ラクトンを基盤とするビタミンD受容体アンタゴニストの設計と合成」
齋藤　望、橘高敦史
有機合成化学協会誌 65 (10) 947-958 (2007).
116.
 Kinetic Studies of 25-Hydroxy-19-Nor-Vitamin D3 and 1a,25-Dihydroxy-19-Nor-Vitamin D3 Hydroxylation by CYP27B1 and CYP24A1;
Urushino, N., Nakabayashi, S., Arai, M. A., Kittaka, A., Chen, T. C., Yamamoto, K., Hayashi, K., Kato, S., Ohta, M., Kamakura, M., Ikushiro, S., Sakaki, T.
Drug Metab. Dispos. 35 (9) 1482-1488 (2007).
117.
 "High-Throughput System for Analyzing Ligand-Induced Cofactor Recruitment by Vitamin D Receptor"
Arai, M. A., Takeyama, K., Ito, S., Kato, S., Chen, T. C., Kittaka, A.
Bioconjugate Chem. 18 (3) 614-620 (2007).
118.
 "Creative Synthesis of Novel Vitamin D Analogs for Health and Disease"
Kittaka, A., Saito, N., Honzawa, S., Takenouchi, K., Ishizuka, S., Chen, T. C., Peleg, S., Kato S., Arai, M.A.
J. Steroid Biochem. Mol. Biol. 103 (3) 269-276 (2007).
119.
 "Evaluation of C-2-Substituted 19-Nor-1ｱ,25-dihydroxyvitamin D3 Analogs as Therapeutic Agents for Prostate Cancer"
Chen, T.C., Persons, K.S., Zheng, S., Mathieu, J., Holick, M.F., Lee, Y.F., Bao, B., Arai, M.A., Kittaka, A.
J. Steroid Biochem. Mol. Biol. 103 (3) 717-720 (2007).
120.
 "Synthesis and Biological Evaluation of Several Structural Analogs of 2-Arachidonoylglycerol, an Endogenous Cannabinoid Receptor Ligand"
Suhara, Y., Oka, S., Kittaka, A., Takayama, H., Waku, K., Sugiura, T.
Bioorg. Med. Chem. 15 (2) 854-867 (2007).
121.
 "Further Synthetic and Biological Studies on Vitamin D Hormone Antagonists Based on C24-Alkylation and C2α-Functionalization of 25-Dehydro-1α-hydroxyvitamin D3-26,23-lactones"
Saito, N., Matsunaga, T., Saito, H., Anzai, M., Takenouchi, K., Miura, D., Namekawa, J., Ishizuka, S., Kittaka, A.
J. Med. Chem. 49 (24) 7063-7075 (2006).
122.
 "Highly Potent Vitamin D Antagonists: Design, Synthesis and Biological Evaluation"
Saito, N., Kittaka, A.
ChemBioChem 7 (10) 1478-1490 (2006).
123.
 "Biological Activities of 2ｱ-Substituted Analogues of 1ｱ,25-Dihydroxyvitamin D3 in Transcriptional Regulation and Human Promyelocytic Leukemia (HL-60) Cell Proliferation and Differentiation"
Takahashi, E., Nakagawa, K., Suhara, Y., Kittaka, A., Nihei, K., Konno, K., Takayama, H., Ozono, K., Okano T.
Biol. Pharm. Bull. 29 (11) 2246-2250 (2006).
124.
 "Sequence-specific Recognition of Double-Stranded DNA by Cooperative Strand Invasion"
Sugiyama, T., Imamura, Y., Hakamata, W., Kurihara, M., Kittaka, A.
Nucleic Acids Symp. Ser. (No. 50) 157-158 (2006).
125.
 "Probing a Water Channel near the A-Ring of Receptor-Bound 1α,25-Dihydroxyvitamin D3 with Selected 2α-Sunstituted Analogues"
Hourai, S., Fujishima, T., Kittaka, A., Suhara, Y., Takayama, H., Rochel, N., Moras, D
J. Med. Chem. 49 (17) 5199-5205 (2006).
126.
 "Efficient Synthesis of Carbopeptoid Oligomers: Insight into Mimicry of β-Peptide"
Suhara, Y., Kurihara, M., Kittaka, A., Ichikawa, Y.
Tetrahedron 62 (34) 8207-8217 (2006).
127.
 "Recent Progress of Study on Vitamin D Analogs"
Kittaka, A., Saito, N., Takano, M.
Clinical Calcium 16 (7) 1154-1165 (2006).
128.
 "Recent Results on A-Ring Modification of 1α,25-Dihydroxyvitamin D3: Design and Synthesis of VDR-Agonists and Antagonists with High Biological Activity"
Saito, N., Honzawa, S., Kittaka, A.
Curr. Top. Med. Chem. 6 (12), 1273-1288 (2006).
129.
 "Novel 2-Alkyl-1α,25-dihydroxy-19-norvitamin D3: Efficient Synthesis with Julia Olefination, Evaluation of Biological Activity, and Development of New Analyzing System for Co-activator Recruitment"
Arai, M. A., Kittaka, A.
Anticancer Res. 26 (4), 2621-2632 (2006).
130.
 "Methyl-introduced A-ring Analogues of 1α,25-Dihydroxyvitamin D3: Synthesis and Biological Evaluation"
Fujishima, T., Tsutsumi, R., Negishi, Y., Fujii, S., Takayama, H., Kittaka, A., Kurihara, M
Anticancer Res. 26 (4) 2633-2636 (2006).
131.
 "Synthsis and 2α-Modification of 24-Phenylvitamin D3 Lactones: Effects on VDR Antagonistic Activity"
Saito, N., Matsunaga, T., Saito, H., Anzai, M., Takenouchi, K., Miura, D., Ishizuka, S., Takayama, H., Kittaka, A
Heterocycles 67 (1), 311-336 (2006).
132.
 "Synthesis of 25-Hydroxy-19-norvitamin D3 Analogs and Their Antiproliferative Activities on Prostate Cells"
Arai, M. A., Tsutsumi, R., Hara, H., Chen, T. C., Sakaki, T., Urushino, N., Inouye, K., Kittaka, A.
Heterocycles 66 (1), 469-479 (2005).
133.
 "Design, Synthesis and Biological Evaluation of Novel 1α,25-Dihydroxyvitamin D3 Analogues Possessing Aromatic Ring on 2α-Position"
Honzawa, S., Hirasaka, K., Yamamoto, Y., Peleg, S., Fujishima, T., Kurihara, M., Saito, N., Kishimoto, S., Sugiura, T., Waku, K., Takayama, H., Kittaka, A.
Tetrahedron 61 (47), 11253-11263 (2005).
134.
 "Synthesis of 24,24-Ethanovitamin D3 Lactones Using Ruthenium-Catalyzed Intermolecular Enyne Metathesis: Potent Vitamin D Receptor Antagonists"
Saito, N., Masuda, M., Saito, H., Takenouchi, K., Seiichi, I., Namekawa, J., Takimoto-Kamimura, M., Kittaka, A.
SYNTHESIS (15), 2533-2543 (2005).
135.
 "Cooperative Strand Invasion of Double-Stranded DNA by Peptide Nucleic Acid"
Sugiyama, T.,Imamura, Y., Hakamata, W., Kurihara, M., Kittaka, A.
Nucleic Acids Symp. Ser. 49, 167-168 (2005).
136.
 "Metabolism of 2α-Propoxy-1α,25-dihydroxyvitamin D3 and 2α-(3-Hydroxypropoxy)-1α,25-dihydroxyvitamin D3 by Human CYP27A1 and CYP24A1"
Abe, D., Sakaki, T., Kusudo, T., Kittaka, A., Saito, N., Suhara, Y., Fujishima, T., Takayama, H., Hamamoto, H., Kamakura, M., Ohta, M., Inouye, K.
Drug Metab. Dispos. 33 (6), 778-784 (2005).
137.
 "The Antagonizm between 2-Methyl-1,25-dihydroxyvitamin D3 and 2-Methyl-20-epi-1,25-dihydroxyvitamin D3 in Non-genomic Pathway-mediated Biological Responses Induced by 1α,25-Dihydroxyvitamin D3 Assessed by NB4 Cell Differentiation"
Miura, D., Norman, A. W., Mizwicky, M. T., Fujishima, T., Konno, K., Kittaka, A., Takayama, H., Ishizuka, S.
J. Steroid Biochem. Mol. Biol. 94 (5), 469-479 (2005).
138.
 "Schiff Base Formation Between 5-Formyl-2'-deoxyuridine and Lysine e-Amino Group at Monomer and Oligomer Levels"
Kittaka, A., Horii, C., Tanaka, H., Miyasaka, T., Nakamura, K. T., Kuroda, R., Sugiyama, T.
Heterocycles 64 (1), 367-382 (2004).
139.
 "Design and Efficient Synthesis of 2α-(ω-Hydroxyalkoxy)-1α,25-dihydroxyvitamin D3 Including 2-epi-ED-71 and Its 20-Epimers with HL-60 Cell Differentiation Activity"
Saito, N., Suhara, Y., Kurihara, M., Fujishima, T., Honzawa, S., Takayanagi, H., Kozono, T., Matsumoto, M., Ohmori, M., Miyata, N., Takayama, H., Kittaka, A.
J. Org. Chem. 69 (22), 7463-7471 (2004).
140.
 "Topological Stabilization of PNA-DNA Invasion Complex"
Sugiyama, T., Kuroda, R., Kittaka, A.
Nucleic Acids Symp. Ser. 48, 39-40 (2004).
141.
 "24,24-Dimethylvitamin D3-26,23-lactones and Their 2α-Functionalized Analogues as Highly Potent VDR Antagonists"
Saito, N., Masuda, M., Matsunaga, T., Saito, H., Anzai, M., Takenouchi, K., Miura, D., Ishizuka, S., Takimoto-Kamimura, M., Kittaka, A.
Tetrahedron 60 (36), 7951-7961 (2004).
142.
 "Metabolism of A-Ring Diastereomers of 1α,25-Dihydroxyvitamin D3 by CYP24A1"
Kusudo, T., Sakaki, T., Abe, D., Fujishima, T., Kittaka, A., Takayama, H., Hatakeyama, S., Ohta, M., Inouye, K.
Biochem. Biophys. Res. Commun. 321 (4), 774-782 (2004).
143.
 "Synthesis of PNA Using a Fmoc/Boc Protecting Group Strategy"
Sugiyama, T., Kittaka, A., Takemoto, Y., Kuroda, R.
Peptide Science 2003, 447-448 (2004).
144.
 "2,2-Functionalized Analogues of 1α,25-Dihydroxyvitamin D3, The Potent Inducers of Cell Differentiation"
Fujishima, T., Kittaka, A., Kurihara, M., Saito, N., Honzawa, S., Kishimoto, S., Sugiura, T., Waku, K., Takayama, H.
J. Steroid Biochem. Mol. Biol. 89-90 (May), 89-92 (2004).
145.
 "Synthesis of Novel 1α,25-Dihydroxy-19-norvitamin D3 with an Amide Conjugate"
Suhara, Y., Ono, K., Yoshida, A., Fujishima, T., Saito, N., Honzawa, S., Kishimoto, S., Sugiura, T., Waku, K., Takayama, H., Kittaka, A.
Heterocycles 62 (1), 423-436 (2004).
146.
 "Dramatic Enhancement of Antagonistic Activity on Vitamin D Receptor: A Double Functionalization of 1α-Hydroxyvitamin D3 26,23-Lactones"
Saito, N., Saito, H., Anzai, M., Yoshida, A., Fujishima, T., Takenouchi, K., Miura, D., Ishizuka, S., Takayama, H., Kittaka, A.
Org. Lett. 5 (25), 4859-4862 (2003).
147.
 "Remarkable Effect of 2α-Modification on the VDR Antagonistic Activity of 1α-Hydroxyvitamin D3-26,23-Lactones"
Saito, N., Matsunaga, T., Fujishima, T., Anzai, M., Saito, H., Takenouchi, K., Miura, D., Ishizuka, S., Takayama, H., Kittaka, A.
Org. Biomol. Chem. 1 (24), 4396-4402 (2003).
148.
 Metabolism of 20-Epimer of 1α,25-Dihydroxyvitamin D3 by CYP24: Species-based Difference between Humans and Rats"
Kusudo, T., Sakaki, T., Daisuke, A., Fujishima, T., Kittaka, A., Takayama, H., Ohta, M., Inoue, K.
Biochem. Biophys. Res. Commun. 309 (4), 885-892 (2003).
149.
 "Synthesis of a A-Ring Synthon of 2α-Sunstituted Vitamin D3 Analogues Utilizing Grignard Reaction Towards Methyl 2,3-Anhydro-4,6-O-benzylidene-a-D-mannopyranoside"
Honzawa, S., Yamamoto, Y., Hirasaka, K., Takayama, H., Kittaka, A.
Heterocycles 61 (30 th Anniversary Issue), 327-338 (2003).
150.
 "Synthesis of 2-Modified 1α,25-Dihydroxy-19-norvitamin D3 with Julia Olefination: High Potency in Induction of Differentiation on HL-60 Cells"
Ono, K., Yoshida, A., Saito, N., Fujishima, T., Honzawa, S., Suhara, Y., Kishimoto, S., Sugiura, T., Waku, K., Takayama, T., Kittaka, A.
J. Org. Chem. 68 (19), 7407-7415 (2003).
151.
 "Concise Synthesis and Biological Activities of 2α-Alkyl- and 2α-(ω-Hydroxyalkyl)-20-epi-1α,25-Dihydroxyvitamin D3"
Honzawa, S., Suhara, Y., Nihei, K., Saito, N., Kishimoto, S., Fujishima, T., Kurihara, M., Sugiura, T., Waku, K., Takayama, H., Kittaka, A.
Bioorg. Med. Chem. Lett. 13 (20), 3503-3506 (2003).
152.
 "Aggregation of RecA-derived Peptides on Single-stranded Oligonucleotides Triggered by Schiff base-mediated Crosslinking"
Sugiyama, T., Kittaka, A., Takayama, H., Tomioka, M., Ida, Y., Kuroda, R.
Bioorg. Med. Chem. Lett. 13 (17), 2847-2851 (2003).
153.
 "Design and Synthesis of Potent Vitamin D Receptor Antagonists with A-Ring Modifications: Remarkable Effects of 2α-Methyl Introduction on Antagonistic Activity"
Fujishima, T., Kojima, Y., Azumaya, I., Kittaka, A., Takayama, H.
Bioorg. Med. Chem. 11 (17), 3621-3631 (2003).
154.
 "Efficient and Convergent Coupling Route for the Short-step Synthesis of Enantio-pure 2α- and 2β-Alkylated 1α,25-Dihydroxy-19-norvitamin D3 Analogues"
Yoshida, A., Ono, K. Suhara, Y., Saito, N., Takayama, H., Kittaka, A.
SYNLETT (8), 1175-1179 (2003).
155.
 "Synthesis of 2,2-Dimethyl-1,25-dihydroxyvitamin D3: A-Ring Structural Motif that Modulates Interactions of Vitamin D Receptor with Transcriptional Cofactors"
Fujishima, T., Kittaka, A., Yamaoka, K., Takeyama, K., Kato, S., Takayama, H.
Org. Biomol. Chem. 1 (11), 1863-1869 (2003).
156.
 "2α-(3-Hydroxypropyl)- and 2α-(3-Hydroxypropoxy)-1α,25-dihydroxyvitamin D3 Accessible to Vitamin D Receptor Mutant Related to Hereditary Vitamin D-Resistant Rickets"
Kittaka, A., Kurihara, M., Peleg, S., Suhara, Y., Takayama, H.
Chem. Pharm. Bull. 51 (3), 357-358 (2003).
157.
 "Synthesis of Oligonucleotides with 6-Formyl-2'-O-methyluridine and Thermal Stability of Their Duplexes"
Kittaka, A., Kuze, T., Sarai, A., Takayama, H., Tanaka, H., Miyasaka, T., Inoue, J., Ishii, S.
Heterocycles 59 (1), 207-215 (2003).
158.
 "A環修飾活性型ビタミンD3の合成と活性"
高山浩明、橘高敦史、藤島利江、須原義智
有機合成化学協会誌 60 (4), 370-381 (2002).
159.
 "活性型ビタミンD3のＡ環修飾、特に２位の官能基化と生物活性"
高山浩明、橘高敦史、藤島利江、須原義智
ビタミン 76 (11), 491-505 (2002).
160.
"Synthesis of PNA Using a Fmoc/Boc Protecting Group Strategy"
Sugiyama, T., Kittaka, A., Takemoto, Y., Takayama, H., Kuroda, R.
Nucleic Acids Res. Suppl. (No. 2), 145-146 (2002).
161.
 "Design and Efficient Synthesis of New Stable 1α,25-Dihydroxy-19-norvitamin D3 Analogues Containing Amide Bond"
Suhara, Y., Kittaka, A., Ono, K., Kurihara, M., Fujishima, T., Yoshida, A., Takayama, H.
Bioorg. Med. Chem. Lett. 12 (24), 3533-3536 (2002).
162.
 "Synthesis and Testing of 2α-Modified 1α,25-Dihydroxyvitamin D3 Analogues with a Double Side Chain: Marked Cell Differentiation Activity"
Suhara, Y., Kittaka, A., Kishimoto, S., Calverley, M. J., Fujishima, T., Saito, N., Sugiura, T., Waku, K. Takayama, H.
Bioorg. Med. Chem. Lett. 12 (22), 3255-3258 (2002).
著書リスト・その他
1.
 橘高敦史　編著
「創薬科学・医薬化学（第2版）」
化学同人（京都） 2022年10月30日発行．ISBN 978-4-7598-2332-5
2.
 川越文裕、橘高敦史
「フッ素化ビタミンD誘導体の化学」
ビタミン2022, 96 (7), 296-304.
3.
  川越文裕、本谷小佑里、橘高敦史
「フッ素化ビタミンD3の効率的合成法」
アグリバイオ 2021, 5 (11), 964-969.
4.
  橘高敦史　分担執筆
「ビタミン・バイオファクター総合事典」
日本ビタミン学会編　朝倉書店（東京）2021年7月1日発行．
ISBN 978-4-254-10292-5 C3540
5.
 橘高敦史　名称委員会分担作成
第十八改正日本薬局方
厚生労働省　令和3年6月7日発行．（2021年）
6.
 真野寛生、生城真一、高野真史、橘高敦史、榊　利之
「VDRリガンドに応答して発光量が劇的に上昇する分割型ルシフェラーゼバイオセンサーの開発」
ビタミン 2020, 94 (5,6), 307-313.
7.
 丸田　浩、安井文彦、橘高敦史、小原道法
「COVID-19の食餌対策～PAKを遮断する野菜や食物成分～」
食品と科学 2020, (11), 59-64.
8.
 橘高敦史　分担訳
「ダンラップ・ヒューリン 創薬化学」
13章 中枢神経系に作用する医薬品 他
［監訳］長野哲雄
［翻訳］井上英史、金光佳世子、橘高敦史、島田逸郎、鈴木紀行、永持雅敏、
西川知之、平野智也、安田公助
東京化学同人（東京）2020年3月24日発行．ISBN 978-4-8079-0993-3
9.
 橘高敦史
「ビタミンD構造異性体タキステロールと類縁体の化学」
ビタミン 2020, 94 (3), 155-161.
10.
 橘高敦史　編著
「知っておきたい有機反応100」第２版
［編集］望月正隆、大和田智彦、橘高敦史、増野匡彦
東京化学同人（東京）2019年3月26日発行．
ISBN 978-4-8079-0960-5
11.
 橘高敦史　編著
「新・毒物劇物取扱の手引」
［監修］大野泰雄［編集］益山光一
［編集協力］栗原正明 橘高敦史 髙橋祐次 黒木由美子
時事通信社（東京）2018年6月20日発行．
ISBN978-4-7887-1550-9
12.
 橘高敦史　領域担当編集
スタンダード薬学シリーズⅡ ３　化学系薬学Ⅲ.「自然が生み出す薬物」
日本薬学会編　東京化学同人（東京）2016年10月5日発行．
ISBN978-4-8079-1707-5　C3347
13.
 橘高敦史
「ビタミンD誘導体合成：制がんおよび骨形成活性への効果」
ビタミン 2017, 91 (3), 174-181.
14.
 真野寛生、生城真一、高野真史、橘高敦史、榊　利之
「分割型ルシフェラーゼを用いたビタミンD受容体リガンド検出系の構築および化合物スクリーニングへの応用」
ビタミン 2017, 91 (3), 165-172.
15.
 三澤隆史、出水庸介、谷内出友美、大岡伸通、野尻久雄、橘高敦史、槇島　誠、内藤幹彦、栗原正明
「ビタミンD受容体(VDR)の活性を制御するノンセコステロイド型VDRリガンドの創製」
ビタミン 2017, 91 (2), 113-120.
16.
 橘高敦史　領域担当編集・著
スタンダード薬学シリーズⅡ ３　化学系薬学Ⅱ.「生体分子・医薬品の化学による理解」
日本薬学会編　東京化学同人（東京）2016年3月26日発行．
ISBN978-4-8079-1706-8　C3347
17.
 Atsushi Kittaka, Masashi Takano, and Hiroshi Saitoh
“Vitamin D Analogs with Nitrogen Atom at C2 Substitution and Effect on Bone Formation”
In Vitamins and Hormones Vol. 100, Gerald Litwack ed.; Elsevier Academic Press, 2016, pp.379-394.
ISBN: 978-0-12-804824-5, doi.org/10.1016/bs.vh.2015.10.010
18.
 Eiji Munetsuna, Atsushi Kittaka, Tai C. Chen, and Toshiyuki Sakaki
“Metabolism and Action of 25-Hydroxy-19-nor-Vitamin D3 in Human Prostate Cells”
In Vitamins and Hormones Vol. 100, Gerald Litwack ed.; Elsevier Academic Press, 2016, pp.357-377.
ISBN: 978-0-12-804824-5, doi.org/10.1016/bs.vh.2015.10.009
19.
 橘高敦史　領域担当編集　スタンダード薬学シリーズⅡ ３　化学系薬学Ⅰ.「化学物質の性質と反応」　日本薬学会編　東京化学同人（東京）2015年2月20日発行．ISBN978-4-8079-1705-1　C3347
20.
 橘高敦史、澤田大介　「ビタミンD受容体リガンドの創製」　ファルマシア 2015, 51(3), 196-200.
21.
 橘高敦史　分担執筆 「ビタミンDと疾患～基礎の理解と臨床への応用～」 岡野登志夫編　医薬ジャーナル社（大阪） 2014年1月15日発行． ISBN 978-4-7532-2656-2 C3047
22.
 橘高敦史　分担執筆 「薬学用語辞典」 日本薬学会編　東京化学同人（東京）2012年3月23日発行． ISBN 978-4-8097-0677-2 C3547
23.
 橘高敦史　分担執筆 「ビタミン総合事典」 日本ビタミン学会編　朝倉書店（東京）2010年11月25日発行． ISBN 978-4-254-10228-4 C3540
24.
 橘高敦史　分担執筆 スタンダード薬学シリーズ３　化学系薬学Ⅳ.「演習編」　第Ⅰ部13章、15章（SBO 75,76）、第Ⅱ部1章（SBO 7, 8, 9）． 日本薬学会編　東京化学同人（東京）2007年12月14日発行． ISBN978-4-8079-1470-8
25.
 橘高敦史　編著 「創薬科学・医薬化学」　14章 抗菌薬、15章 抗がん剤、16章 抗エイズ薬、17章 骨粗鬆症治療薬と高齢化249 － 297ページ． 株式会社化学同人（京都）2007年10月20日発行． ISBN978-4-7598-1256-5
26.
 橘高敦史　編著 「知っておきたい有機反応100」（編集委員） Ⅶ「芳香族求電子置換反応」141 － 158ページ、Ⅷ「芳香族求核置換反応」159 － 165ページ． 日本薬学会編　東京化学同人（東京）2006年1月10日発行． ISBN 4-8079-0628-3.
27.
 橘高敦史　分担執筆 スタンダード薬学シリーズ３　化学系薬学Ⅱ.「ターゲット分子の合成と生体分子・医薬品の化学」　SBO 24, 27, 28, 50． 日本薬学会編　東京化学同人（東京）2005年9月13日発行． ISBN 4-8079-1455-3.
28.
 橘高敦史　分担翻訳 「受容体での薬物作用」（翻訳）メディシナルケミストリー　第５章・64 ? 90ページ． 北川　勲・柴崎正勝・富岡　清　監訳 丸善株式会社（東京・日本橋）平成１５年３月３１日発行． ISBN 4-621-07187-4.
29.
 Hiroaki Takayama, Atsushi Kittaka, Toshie Fujishima, and Yoshitomo Suhara“Design, Synthesis, and Biological Studies of the A-Ring Modified 1,25-Dihydroxyvitamin D3 Analogs” In Recent Results in Cancer Research Vol. 164, Vitamin D analogs in cancer prevention and therapy Reichrath J., Fridrich M., Tilgen W. Eds.; Springer-Verlag: Berlin Heidelberg, Germany, 2003 pp 289-317.ISBN 3-540-00290-1.
30.
 Drug Action at Receptors; Kittaka, A. (Japanese Ed. 2003 by Maruzen Co. Ltd., Tokyo) Chapter 5,pp 64-90, In An Introduction to Medicinal Chemistry by Patrick G. L., Second Ed. Oxford University Press, Oxford (2001).
31.
 Facile Synthesis of 2a-(Hydroxyalkoxy)-1a,25-dihydroxyvitamin D3; Kittaka, A., Suhara, Y., Takayanagi, H., Fujishima, T., Kurihara, M., Takayama, H: Vitamin D Endocrine System: Structural, Biological, Genetic and Clinical Aspects, pp 49-52, Eds. Norman, A. W., Bouillon R., Thomasset M. University of California, Printing and Reprographics (2000).
32.
 Man-Designed Bleomycin Based on the Antitumor Mechanism of Bleomycin; Otsuka, M., Kittaka, A., Sugano, Y., Owa, T., Ohno, M., Sugiura, Y., Umezawa, H: In Peptide Chemistry 1987; Proceedings of Japan Symposium on Peptide Chemistry, pp 615-620, Eds. by Shiba, T., Sakakibara, S; Protein Research Foundation, Osaka (1988).