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Publication | Japanese | |||
Laboratory of Pharmaceutical Bioscience | ||||
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Outline of Research | |||
Introduction Established in April 2024, the Laboratory of Pharmaceutical Bioscience evolved from the former Laboratory of Molecular Pharmaceutics. Using techniques from cell biology, biochemistry, and molecular biology, our focus lies in understanding immune system phenomena and developing new technologies, aligning with regulatory science principles. Research Overview The immune system defends against infections and cancer, yet excessive responses can cause allergies and severe adverse drug reactions. Many autoimmune diseases are intractable, underscoring the social importance of studying undesirable immune responses. Our research also delves into macrophages and neutrophils' roles in bacterial infections and cancer metastasis, aiming to develop novel vaccines and anticancer drugs through molecular mechanisms. Educational Activities In addition to research, we are also involved in teaching courses related to regulatory science, including the pharmaceutical affairs act and drug information science. We also conduct practical training and exercises in pharmaceutical sciences and related fields. Research Themes 1. Developing the EXiLE method, an allergy test using cultured cells 2. Studying human leukocyte antigens (HLA) in severe adverse drug reactions prediction 3. Investigating intracellular lipid metabolism in bacterial infections 4. Unraveling mechanisms of malignancy progression in human breast cancer cells 5. Regulatory science research on integrating pharmacogenomics into drug package inserts |
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Staff | |||
Professor |
Ryosuke, Nakamura Ph.D. | |||
Senior Assistant Professor |
Kazunari Tanigawa, Ph.D. | |||
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Fellow・Graduate Student | |||
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